Is a Molded Glass Lens A Viable Option for Your Next Medical Device

The use of point of care (POC) devices is growing as healthcare markets address the need for more real time analysis in applications such as pharmaceutical interventions and diagnosis of infectious diseases. Additionally, emerging technology coupled with reduced healthcare costs drive POC solutions that result in better patient outcomes that may be deployed globally.

POC devices also allow a more patient focused approach and self-monitoring which leads to more effective care.  The trend of adapting larger centralized lab devices for use in patient monitoring and diagnosis is well documented for hematology and bio-chemistry applications.  However, shrinking clinical lab tools to a usable POC or bench top device delivering equal or improved analytical performance is challenging.

Athelas,, Mountain View, CA, developing the next generation of immune POC devices, sought a new approach for monitoring white blood cells (WBC) and neutrophil percent (NEUT% ) using a finger prick of blood.  The traditional approach used coulter counting or flow cytometry-based tools.  The Athelas One device uses computer vision with custom optics for high precision analysis based on blood cell imaging.

Looking to improve precision in cellular identification, Athelas, worked with FISBA,, based in Portland, ME, to redesign the optical path and improve image size and resolution.

Athelas and FISBA collaborated on the development of a unique optical architecture using a combination of off-the-shelf components. The optical path length was reduced by more than 2x and the field-of-view was increased by 30%. Using agile development techniques, more than 4 hardware iterations were completed in 3 months. The design was transferred, and the client has begun building pre-production prototypes.  The Athelas One is now FDA Cleared for WBC and NEUT% monitoring in point-of-care settings.

Coupling machine learning and AI with innovative optical-mechanical designs for diagnostic devices will advance point of care testing globally.  As with the Athelas One, the ability to replicate lab size diagnostic machine performance, at the point of care, improves patient outcomes and advances major initiatives in companies and communities devoted to living better lives.

Customer Testimonial:

“It is rare to find standout talent like the team at FISBA. Our collaboration with FISBA achieved many exciting firsts. The Founder, Dan Gray was great at strategic planning and had the grit and resourcefulness to facilitate the development of a robust, easy-to-integrate solution. Dan is an accomplished optics expert and doubles as a fantastic mentor: taking the time to explain specialized analytical concepts in a relatable way. His strong attention to detail has been valuable when technical challenges arise and we have thorough documentation for why and how we went about design iterations. FISBA is a highly recommended development team.”


Related Postings